Vertera Spine’s COHERE Fusion Device Wins Award For Best Spine Technologies for 2016

ATLANTA, Nov. 21, 2016 /PRNewswire/ — Vertera Spine, a developer of medical devices using advanced biomaterial technologies, today announced that the COHERE® Cervical Interbody Fusion Device has been recognized by Orthopedics This Week as one of the Top Ten Best Spine Technologies for 2016. COHERE features Vertera Spine’s patented porous PEEK (polyetheretherketone) Scoria®biomaterial technology, a porous architecture that seamlessly integrates with solid PEEK to mimic the cancellous to cortical transition of native bone.

Every year, Orthopedics This Week recognizes the engineering teams and inventors who develop and successfully translate innovative products into clinical use to treat back pain. This year, winning technologies were selected based on creativity, innovation, demonstrated ability to solve a critical clinical problem and their potential long-term impact on improving spine surgery.

While porous metal and porous metal-coated PEEK implants have found their way into spine fusion applications, COHERE is the first and only porous PEEK fusion device to reach clinical use. By having porous PEEK Scoria on the superior and inferior sides, COHERE provides an environment that supports bony tissue ingrowth while retaining the mechanical properties and imaging capabilities of traditional PEEK. COHERE has been available under a limited market release to a select group of surgeons since May 2016.

COHERE was considered a viable recipient of this year’s Spine Technology Award due to the extensive research presented on porous PEEK Scoria. The biomaterial’s mechanical properties and in vitro cellular response are reported in a study recently published in Clinical Orthopaedics and Related Research.1 Performed by researchers at the Georgia Institute of Technology, results of the study show that porous PEEK elicits an elevated in vitro osteogenic response compared with both smooth PEEK and smooth titanium. While prior studies have shown a similar improved osteogenic response on porous titanium, this is the first study to suggest PEEK Scoria’s porous architecture can improve the osteogenic response to PEEK. Furthermore, the study also revealed that porous PEEK Scoria exhibits the appropriate fatigue strength to withstand loading seen in the spine and a higher interfacial shear strength than bone. Likewise, another study recently published in Journal of Mechanical Behavior of Biomedical Materials demonstrates that PEEK Scoria maintains its porous architecture under similar compressive loading seen in the spine while also exhibiting the same wear resistance as regular PEEK.

“We are honored to have our COHERE cervical device with porous PEEK Scoria technology selected amongst an elite group of cutting-edge technologies,” said Stephen Laffoon, Vertera Spine director of Engineering and one of the COHERE device inventors. “The recent publication of studies on porous PEEK Scoria exemplifies our continued commitment to not only validate our own porous PEEK technology, but also advance the fundamental understanding around the role of the implant in driving osseointegration.”

About Vertera Spine:
Vertera Spine is a privately-held medical device company that develops and commercializes multifunctional implants that use or complement its patented porous technology to address critical clinical needs in spine surgery. The company has received funding from the National Science Foundation, Georgia Research Alliance, and Duke Angel Network to translate its growing technology portfolio into commercial products. For more information, visit www.verteraspine.com or call 678.705.9039.

COHERE and Scoria are registered trademarks of Vertera Spine.

1Torstrick FB, Gall K, et al. Do Surface Porosity and Pore Size Influence Mechanical Properties and Cellular Response to PEEK? Clinical Orthopaedics and Related Research, 2016. 474 (11): 2373-2383.

2Evans NT, Gall K, et al. Local deformation behavior of surface porous polyether-ether-ketone. Journal of Mechanical Behavior of Biomedical Materials, 2017. 65: 522-532.

SOURCE Vertera Spine

Related Links

http://www.verteraspine.com

Zimmer Biomet Announces Cash Tender Offers for Up to $1.1 Billion Aggregate Purchase Price of Certain Outstanding Debt Securities

WARSAW, Ind., Nov. 21, 2016 /PRNewswire/ — Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) (the “Company”) today announced the commencement of cash tender offers (collectively, the “Offers”) for up to $1.1 billion aggregate purchase price (excluding accrued and unpaid interest to, but not including, the applicable settlement date and excluding fees and expenses related to the Offers) (the “Maximum Tender Amount”) of its 5.750% Senior Notes due 2039, its 4.450% Senior Notes due 2045, its 4.250% Senior Notes due 2035, its 3.550% Senior Notes due 2025 and its 4.625% Senior Notes due 2019 (collectively, the “Notes”). The purpose of the Offers is to reduce the principal amount of the Company’s outstanding debt securities. Notes purchased in the Offers will be retired and cancelled.

The following table sets forth certain information regarding the Notes and the Offers:

Title of Security

CUSIP
Number

Principal
Amount
Outstanding

Tender Cap(1)

Acceptance
Priority
Level

Reference U.S.
Treasury
Security

Bloomberg
Reference
Page(2)

Fixed Spread
(basis
points)

Early
Tender
Premium
(per $1,000)

Hypothetical Total Consideration (per $1,000)(3)

5.750% Senior Notes due 2039

98956PAB8

$   500,000,000

$250,000,000

1

2.25% UST due 8/15/2046

FIT1

170

$30.00

$1,140.39

4.450% Senior Notes due 2045

98956PAH5

$1,250,000,000

N/A

2

2.25% UST due 8/15/2046

FIT1

170

$30.00

$   954.73

4.250% Senior Notes due 2035

98956PAG7

$   500,000,000

N/A

3

2.25% UST due 8/15/2046

FIT1

155

$30.00

$   957.62

3.550% Senior Notes due 2025

98956PAF9

$2,000,000,000

$200,000,000

4

2.00% UST due 11/15/2026

FIT1

130

$30.00

$   994.70

4.625% Senior Notes due 2019

98956PAA0

$   500,000,000

$200,000,000

5

1.00% UST due 11/15/2019

FIT1

65

$30.00

$1,075.53

(1) The Tender Cap for each series represents the maximum aggregate principal amount of Notes of such series that will be purchased in the Offers.

(2) The applicable page on Bloomberg from which the dealer managers will quote the bid side prices of the applicable U.S. Treasury Security. In the above table, “UST” denotes a U.S. Treasury Security.

(3) The Hypothetical Total Consideration is inclusive of the Early Tender Premium (as defined below) but exclusive of accrued and unpaid interest from the last interest payment date applicable to the relevant series of Notes up to, but not including, the Early Settlement Date (as defined below) and is based on the reference yield of the Reference U.S. Treasury Security as of 11:00 a.m., New York City time, on November 18, 2016. The actual reference yields of the Reference U.S. Treasury Securities will be determined by the dealer managers based on certain quotes available at 11:00 a.m., New York City time, on the price determination date, which is expected to be December 6, 2016.

The Offers are being made pursuant to and are subject to the terms and conditions, including a financing condition, set forth in the Offer to Purchase dated November 21, 2016 (the “Offer to Purchase”) and the related Letter of Transmittal (the “Letter of Transmittal”). The Offers will expire at 11:59 p.m., New York City time, on December 19, 2016, unless extended or earlier terminated by the Company (the “Expiration Date”). Tenders of Notes may be withdrawn at any time at or prior to 5:00 p.m., New York City time, on December 5, 2016 (the “Withdrawal Deadline”), but may not be withdrawn thereafter except in certain limited circumstances where additional withdrawal rights are required by law.
(3) The Hypothetical Total Consideration is inclusive of the Early Tender Premium (as defined below) but exclusive of accrued and unpaid interest from the last interest payment date applicable to the relevant series of Notes up to, but not including, the Early Settlement Date (as defined below) and is based on the reference yield of the Reference U.S. Treasury Security as of 11:00 a.m., New York City time, on November 18, 2016. The actual reference yields of the Reference U.S. Treasury Securities will be determined by the dealer managers based on certain quotes available at 11:00 a.m., New York City time, on the price determination date, which is expected to be December 6, 2016.

The consideration paid in the applicable Offer for each series of Notes that are validly tendered and accepted for purchase will be determined in the manner described in the Offer to Purchase by reference to a fixed spread over the yield to maturity of the applicable U.S. Treasury Security specified in the table above and in the Offer to Purchase (the “Total Consideration”). Holders of Notes that are validly tendered and not validly withdrawn at or prior to 5:00 p.m., New York City time, on December 5, 2016 (the “Early Tender Deadline”) and accepted for purchase will receive the applicable Total Consideration, which includes an early tender premium of $30.00 per $1,000 principal amount of the Notes accepted for purchase (the “Early Tender Premium”). Holders of Notes who validly tender their Notes following the Early Tender Deadline and on or prior to the Expiration Date will only receive the applicable “Tender Offer Consideration” per $1,000 principal amount of any such Notes validly tendered by such holders that are accepted for purchase, which is equal to the applicable Total Consideration minus the Early Tender Premium. The Total Consideration will be determined at 11:00 a.m., New York City time, on December 6, 2016, unless extended by the Company.

Payments for Notes purchased will include accrued and unpaid interest from the last interest payment date applicable to the relevant series of Notes up to, but not including, the applicable settlement date for such Notes accepted for purchase.

The settlement date for Notes that are validly tendered and not validly withdrawn on or prior to the Early Tender Deadline and accepted for purchase is expected to be December 13, 2016 (the “Early Settlement Date”). The settlement date for Notes that are validly tendered following the Early Tender Deadline but on or prior to the Expiration Date and accepted for purchase is expected to be December 20, 2016, the first business day after the Expiration Date (the “Final Settlement Date”), assuming the Maximum Tender Amount of Notes is not purchased on the Early Settlement Date.

Subject to the applicable tender caps specified in the table above (the “Tender Caps”), the Maximum Tender Amount and proration, all Notes validly tendered and not validly withdrawn on or before the Early Tender Deadline having a higher Acceptance Priority Level (with 1 being the highest) will be accepted before any validly tendered Notes having a lower Acceptance Priority Level (with 5 being the lowest), and all Notes validly tendered after the Early Tender Deadline having a higher Acceptance Priority Level will be accepted before any Notes validly tendered after the Early Tender Deadline having a lower Acceptance Priority Level. However, even if the Offers are not fully subscribed as of the Early Tender Deadline, subject to the Tender Caps, the Maximum Tender Amount and proration, Notes validly tendered and not validly withdrawn on or before the Early Tender Deadline will be accepted for purchase in priority to Notes validly tendered after the Early Tender Deadline even if such Notes validly tendered after the Early Tender Deadline have a higher Acceptance Priority Level than Notes validly tendered prior to the Early Tender Deadline. Subject to applicable law, the Company may increase or decrease any Tender Cap without extending the Early Tender Deadline or the Withdrawal Deadline.

Notes of a series may be subject to proration (rounded to avoid the purchase of Notes in a principal amount other than in an integral multiple of $1,000) if the aggregate principal amount of the Notes of such series validly tendered and not validly withdrawn is greater than the applicable Tender Cap or would cause the Maximum Tender Amount to be exceeded. Furthermore, if the Offers are fully subscribed as of the Early Tender Deadline, holders who validly tender Notes following the Early Tender Deadline will not have any of their Notes accepted for payment regardless of Acceptance Priority Level. The Company’s obligation to accept for payment and to pay for the Notes validly tendered in the Offers is subject to the satisfaction or waiver of the conditions, including a financing condition, as described in the Offer to Purchase. The Company reserves the absolute right, subject to applicable law, to: (i) waive any and all conditions to the Offers, including, without limitation, the financing condition; (ii) extend or terminate the Offers; (iii) increase or decrease the Maximum Tender Amount and/or increase, decrease or eliminate one or more of the Tender Caps without extending the Early Tender Deadline or the Withdrawal Deadline; or (iv) otherwise amend the Offers in any respect.

Information Relating to the Offers

J.P. Morgan Securities LLC and Wells Fargo Securities, LLC are acting as the dealer managers for the Offers. The information agent and tender agent for the Offers is D.F. King & Co, Inc. Copies of the Offer to Purchase, Letter of Transmittal and related offering materials are available by contacting D.F. King & Co, Inc. by telephone at (888) 564‑8149 (toll-free) or (212) 269‑5550 (banks and brokers) or by email at zbh@dfking.com. Questions regarding the Offers should be directed to J.P. Morgan Securities LLC, Liability Management Group, at (212) 834-3424 (collect) or (866) 834-4666 (toll-free) or Wells Fargo Securities, LLC, Liability Management Group, at (704) 410-4760 (collect) or (866) 309-6316 (toll‑free).

This press release shall not constitute an offer to sell, a solicitation to buy or an offer to purchase or sell any securities. The Offers are being made only pursuant to the Offer to Purchase and only in such jurisdictions as is permitted under applicable law.

About Zimmer Biomet

Founded in 1927 and headquartered in Warsaw, Indiana, Zimmer Biomet is a global leader in musculoskeletal healthcare. We design, manufacture and market orthopaedic reconstructive products; sports medicine, biologics, extremities and trauma products; office based technologies; spine, craniomaxillofacial and thoracic products; dental implants; and related surgical products.

We collaborate with healthcare professionals around the globe to advance the pace of innovation. Our products and solutions help treat patients suffering from disorders of, or injuries to, bones, joints or supporting soft tissues. Together with healthcare professionals, we help millions of people live better lives.

We have operations in more than 25 countries around the world and sell products in more than 100 countries. For more information, visit www.zimmerbiomet.com, or follow Zimmer Biomet on Twitter at www.twitter.com/zimmerbiomet.

Cautionary Statement Regarding Forward-Looking Statements

This communication contains forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 regarding the cash tender offers for certain outstanding senior notes of the Company. Forward‑looking statements may be identified by the use of forward-looking terms such as “may,” “will,” “expects,” “believes,” “anticipates,” “plans,” “estimates,” “projects,” “assumes,” “guides,” “targets,” “forecasts,” and “seeks” or the negatives of such terms or other variations on such terms or comparable terminology. Such statements are based upon the current beliefs and expectations of management and are subject to significant risks and uncertainties that could cause actual outcomes and results to differ materially. For a list and description of some of such risks and uncertainties, see the Company’s periodic reports filed with the Securities and Exchange Commission (the “SEC”). These factors should not be construed as exhaustive and should be read in conjunction with the other cautionary statements that are included in the Company’s filings with the SEC. The Company disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be set forth in its periodic reports. Accordingly, such forward‑looking statements speak only as of the date made. Readers of this communication are cautioned not to place undue reliance on these forward‑looking statements, since, while management believes the assumptions on which the forward-looking statements are based are reasonable, there can be no assurance that these forward-looking statements will prove to be accurate. This cautionary statement is applicable to all forward-looking statements contained in this communication.

Logo – http://photos.prnewswire.com/prnh/20150624/225371LOGO

SOURCE Zimmer Biomet Holdings, Inc.

Related Links

http://www.zimmerbiomet.com

Reconstructive Knee Replacement Market to Grow 5.5% Annually Through 2020

CLEVELAND, Nov. 21, 2016 /PRNewswire/ — Demand for reconstructive knee replacements is forecast to increase 5.5 percent annually to $5.0 billion in 2020. The rising incidence of severe osteoarthritis conditions in the aging population will underlie gains. Growth will also benefit from improvements in technology and materials, but will be moderated by limits imposed on health insurance reimbursement rates as well as by the availability of non-surgical alternatives to knee replacement, such as hyaluronic acid injections and reinforced braces. These and other trends are presented in Medical Implants in the US, 6th Edition, a new study from The Freedonia Group, a Cleveland-based industry research firm.

The study is available here
http://www.freedoniagroup.com/industry-study/3465/medical-implants-in-the-us-orthopedic-cardiac-other-6th-edition.htm

Since they were introduced in 1974, knee implants have evolved from simple hinged devices to sophisticated, multiple component configurations that mimic the natural action of the knee.  On average, implants make up about 12 to 15 percent of the cost of knee replacement surgery.  Contract prices of knee replacement systems start at about $3,000 for partial reconstructive models and range up to more than $10,000 for rotating platform models.  Average unit prices are expected to decrease gradually due to healthcare cost containment pressures. The most widely used type of reconstructive knee replacement is the fixed-bearing model.  These models cap the tibia with a flat metal component that holds a plastic spacer securely in place. 

Medical Implants in the US, 6th Edition is a comprehensive look at the medical implants market including orthopedic implants (reconstructive joint replacements, orthobiologicals, spinal implants, trauma implants and dental implants; cardiovascular implants (pacing devices, cardiac stents and structural cardiac implants); and other types. 

Related studies include:                
#3446 World Medical Disposables (August 2016)
http://www.freedoniagroup.com/industry-study/3446/world-medical-disposables.htm 
#3421 In Vitro Diagnostic (IVD) Packaging (June 2016)
http://www.freedoniagroup.com/industry-study/3421/in-vitro-diagnostic-ivd-packaging.htm

About The Freedonia Group – The Freedonia Group, a division of MarketResearch.com, is a leading international industrial research company publishing more than 100 studies annually. Since 1985 we have provided research to customers ranging in size from global conglomerates to one-person consulting firms. More than 90% of the industrial companies in the Fortune 500 use Freedonia Group research to help with their strategic planning. Each study includes product and market analyses and forecasts, in-depth discussions of important industry trends, market share information and profiles of the leading industry players. Reports can be purchased at www.freedoniagroup.com and are also available on www.marketresearch.com and www.profound.com.

Press Contact:
Corinne Gangloff
+1 440.684.9600
cgangloff@freedoniagroup.com

Logo – http://photos.prnewswire.com/prnh/20160805/396004LOGO

SOURCE The Freedonia Group

Related Links

http://www.freedoniagroup.com

NUVASIVE: NEW SPINE TECHNOLOGY INTRODUCTIONS

Elizabeth Hofheinz, M.P.H., M.Ed. • Fri, November 18th, 2016

NuVasive, Inc. has just announced that its Integrated Global Alignment (iGA) platform now supports all spinal procedures, including cervical alignment. They have also introduced image enhancement software that allows the surgical staff to significantly reduce exposure to surgical radiation in the operating room (OR).

As indicated in the October 25, 2016 news release, “iGA is a proprietary, procedurally-integrated digital platform of specialized products designed to help surgeons achieve more precise spinal column alignment…”

To address concerns about surgeon and patient radiation exposure, “NuVasive has acquired the LessRay software technology suite from a company called SafeRay Spine…”

Asked to give details on how the technology helps surgeons “calculate, correct, confirm,” Jason Hannon, NuVasive’s president and chief operating officer, told OTW, “To optimize sagittal alignment prior to surgery, we have two software solutions to help surgeons calculate a patients pelvic parameters, Nuvaline and NuvaMap. Nuvaline is a mobile app that works on the iOS platform, with an Android version to come, and NuvaMap is computer based software which provides a more enhanced version of calculating these same parameters. NuvaMap takes the software step further by allowing a surgeon to simulate different surgical options to understand in advance, how different approaches or interbody devices might affect the outcome on a patient’s parameters.

 

READ THE REST HERE

 

Healthcare Robot Shipments to Surpass 10,000 Units Annually by 2021, According to Tractica

November 21, 2016

BOULDER, Colo.–(BUSINESS WIRE)–As the world’s population ages, and with an increasing shortage of physicians and other healthcare professionals, robots will be a growing presence in the healthcare system. At the same time, healthcare providers are attracted to robots due to their ability to reduce the cost of care, offload menial tasks from human personnel, improve the accuracy of repetitive tasks, and enable enhanced forms of therapy and rehabilitation, among other types of use cases. According to a new report from Tractica, healthcare robots deployed in the years ahead will include surgical robots, hospital logistics robots, disinfectant robots, nursing robots, exoskeleton robots used for rehabilitation, robotic prosthetic limbs, and many other potential robot types.

Tractica forecasts that healthcare robot shipments will increase from approximately 3,400 units annually in 2016 to more than 10,500 units per year by 2021. During that period, the market intelligence firm anticipates that revenue for healthcare robots will grow from $1.7 billion in 2016 to $2.8 billion by 2021.

“More than 200 companies are already active in various aspects of the healthcare robotics market,” says principal analyst Wendell Chun. “These industry players are creating highly specialized devices for a wide range of applications, and the use cases will continue to expand as costs decline and healthcare providers recognize the early successes of robots in supporting high-quality care and a range of ancillary services.”

Tractica’s report, “Healthcare Robotics”, analyzes and forecasts the global market for healthcare robots, including surgical, rehabilitation, and hospital robots. Market sizing and forecasts include unit shipment and revenue, segmented by world region, application market, and enabling technologies. The report includes more than 80 profiles of key players in the healthcare robotics sector. An Executive Summary of the report is available for free download on the firm’s website.

About Tractica

Tractica is a market intelligence firm that focuses on human interaction with technology. Tractica’s global market research and consulting services combine qualitative and quantitative research methodologies to provide a comprehensive view of the emerging market opportunities surrounding Artificial Intelligence, Robotics, User Interface Technologies, Wearable Devices, and Digital Health. For more information, visit www.tractica.com or call +1.303.248.3000.

Contacts

Tractica
Clint Wheelock, +1-303-248-3000
press@tractica.com

Why Bundled Payments for Joint Replacement May Be Risky for Patients?

By Michael Wong, JD, Co-authored with Lynn Razzano, RN, MSN, ONCC, November 18,2016

According to the Centers for Medicare & Medicaid Services (CMS), hip and knee replacements are the most common inpatient surgery for Medicare beneficiaries. In 2014, there were more than 400,000 procedures, costing more than $7 billion for the hospitalizations. CMS says that there is little consistency across providers in terms of the quality and cost of care for these procedures.

With an aim to improve the consistency of the quality and cost of care among providers,  CMS has introduced a new payment model, Comprehensive Care for Joint Replacement (CJR), in April 2016, using a concept known as bundled payments.

A significant aspect of this new model is that it contains exceptions to what will be reimbursed—exceptions that could prove potentially harmful to patients recovering from hip and knee replacements. Reconsidering these exceptions could go a long way in improving patient safety, reducing the number of readmissions, and reducing the cost of care for patients undergoing hip and knee replacement.

Comprehensive care for joint replacement (CJR): How it works

To understand how CJR works and its implications on patient care, it is helpful to understand how the system currently operates.

Consider a scenario:

A patient is admitted to a hospital and the doctor recommends undergoing surgery for major joint replacement (the example would also hold true in the event of the reattachment of a lower extremity). The patient goes into surgery, is then hospitalized after the operation, gets discharged, and continues her recovery from home.

The quality and cost of this episode of care—surgery, hospitalization, and recovery—varies considerably from hospital to hospital. For instance, according to the CMS, the rate of complications (e.g., infections, implant failures) can be three times as high at some hospitals, putting those patients cared for at increased risk. Simultaneously, the cost could range anywhere from $16,500 to $33,000 under the current fee-for-service model.

Under the CJR model, CMS provides bundled payments to hospitals for these kinds of surgeries. Bundled payment is the reimbursement of healthcare providers based on the expected costs of a clinically-defined episode of care like the one described above. It has been estimated that one-third of healthcare costs recovered by hospitals are through bundled payments, and that figure is increasing.

With CJR, CMS reimbursement includes all related items and services paid under Medicare Part A (e.g., inpatient hospital care, skilled nursing facility, hospice, lab tests, surgery, and home health care) and under Medicare Part B (e.g. outpatient care, durable medical equipment, home health care, and some preventive services), with certain exceptions.

 

 

READ THE REST HERE

 

NuVasive to Participate in the Piper Jaffray 28th Annual Healthcare Conference

SAN DIEGO, CA–(Marketwired – November 17, 2016) – NuVasive, Inc. (NASDAQ: NUVA), a leading medical device company focused on transforming spine surgery with minimally disruptive, procedurally-integrated solutions, announced today that management will be presenting at the Piper Jaffray 28th Annual Healthcare Conference at the Lotte New York Palace in New York City on Tuesday, November 29 at 11:00 a.m. ET / 8 a.m. PT.

A live webcast of the presentation will be available online from the Investor Relations page of the Company’s website at nuvasive.com. A replay of the presentation will remain available on the website for 30 days after the applicable live webcast.

About NuVasive
NuVasive, Inc. (NASDAQ: NUVA) is a world leader in minimally invasive, procedurally-integrated spine solutions. From complex spinal deformity to degenerative spinal conditions, NuVasive is transforming spine surgery with innovative technologies designed to deliver reproducible and clinically proven surgical outcomes. NuVasive’s highly differentiated, procedurally-integrated solutions include access instruments, implantable hardware and software systems for surgical planning and reconciliation technology that centers on achieving the global alignment of the spine. With $811 million in revenues (2015), NuVasive has an approximate 2,200 person workforce in more than 40 countries around the world. For more information, please visit nuvasive.com.

Forward-Looking Statements
NuVasive cautions you that statements included in this news release that are not a description of historical facts are forward-looking statements that involve risks, uncertainties, assumptions and other factors which, if they do not materialize or prove correct, could cause NuVasive’s results to differ materially from historical results or those expressed or implied by such forward-looking statements. The potential risks and uncertainties which contribute to the uncertain nature of these statements include, among others, risks associated with acceptance of the Company’s surgical products and procedures by spine surgeons, development and acceptance of new products or product enhancements, clinical and statistical verification of the benefits achieved via the use of NuVasive’s products (including the iGA™ platform), the Company’s ability to effectually manage inventory as it continues to release new products, its ability to recruit and retain management and key personnel, and the other risks and uncertainties described in NuVasive’s news releases and periodic filings with the Securities and Exchange Commission. NuVasive’s public filings with the Securities and Exchange Commission are available at www.sec.gov. NuVasive assumes no obligation to update any forward-looking statement to reflect events or circumstances arising after the date on which it was made.

CONTACT INFORMATION

  • Investor Contact:
    Suzanne Hatcher
    NuVasive, Inc.
    858-458-2240
    Email contact


    Media Contact:
    Michael Farrington
    NuVasive, Inc.
    858-909-1940
    Email contact

Mizuho OSI and Trilux Medical Join Forces for the First Time at MEDICA 2016, Proving Their Commitment to Providing Global Innovative Operating Room Solutions

November 17, 2016

UNION CITY, Calif.–(BUSINESS WIRE)–Mizuho OSI, the leading manufacturer of specialty surgical tables for spinal and orthopaedic trauma surgery and comprehensive imaging procedures, today announced their joint participation with Trilux Medical at MEDICA 2016 World Forum for Medicine in Düsseldorf Germany, November 14-17. Trilux Medical’s surgical light, pendants, and digital OR video and patient information integration equipment compliments Mizuho OSI’s portfolio of specialty surgical and general surgery tables by improving patient outcomes and delivering enhanced clinical value.

While at MEDICA, Trilux Medical, a subsidiary of the Mizuho OSI, showcased its new generation of extremely efficient and ergonomic OR lights. The Aurinio Wave is the only Operating Room light with reLED technology, providing a combination of a shadow-free illuminated field with unique depth and high color rendering. This new dimension of light enables OR teams to work with an impressive light column that allows precise focusing for illuminating deep wounds in any position. Its high-performance level, as well as simple embedding in an existing OR integration system – Paramon – makes the Aurinio Wave the ideal light source for discerning surgeons.

Trilux Medical, a Mizuho OSI company, has 100 years of experience with lighting and technology and 50 years of expertise in operating rooms and intensive care rooms combined. The company is committed to the identification of tasks, the development of ideas, and tailored specific solutions in medical technology.

Mizuho OSI is a US-based company and the leader in the markets for specialty surgery and patient positioning. For 35 years, physicians have relied on Mizuho OSI for innovative surgical tables that provide cost effective and creative solutions. The company’s portfolio includes specialty surgical tables for procedure-specific approaches that improve patient outcomes in spine and orthopedic surgeries, as well as a range of general surgical tables along with disposable and reusable surgical patient care products.

Greg Neukirch, Mizuho OSI’s Vice President of Marketing and Sales, said, “We are thrilled with this opportunity to display our products along with Trilux Medical. The compliment of products illustrates our long-term commitment to providing innovative operating room solutions.”

“MEDICA is the world’s leading trade fair for the medical industry and a perfect venue to show our organization’s dedication to understanding the needs and exceeding the expectations of our global healthcare customers,” said Ozgur Yurduozler, Director of Marketing and Product Management at Trilux Medical.

About Mizuho OSI

For over 35 years Mizuho OSI has developed healthcare products that have allowed medical professionals to better care for their patients. The largest segment of Mizuho OSI’s business focuses on specialty surgical tables that improve surgery through advanced patient positioning. The company is the leading manufacturer of specialty surgical tables for spinal and orthopedic trauma surgery as well as comprehensive imaging procedures. Mizuho OSI was founded in 1978 as Orthopedics Systems, Inc., and is now a subsidiary of the Mizuho Ikakogyo Co., Ltd., in Tokyo, Japan. Mizuho Ikakogyo was founded in 1919 and is the leading general surgical table manufacturer in Japan and Asia. Mizuho OSI is the leading orthopedic and spinal surgical table manufacturer worldwide. Mizuho OSI products are sold in the U.S. through direct sales representatives and worldwide through authorized international distributors. More information is available at: www.mizuhosi.com

Contacts

Mizuho OSI
Kevin McCallum, 510-364-7586
kmcallum@mizuhosi.com
or
Melodie Shubat, 510-298-2615
mshubat@mizuhosi.com

SHS invests in innovative 3D printing specialist – Emerging Implant Technologies (EIT) receives growth financing

TÜBINGEN & TUTTLINGEN, Germany–(BUSINESS WIRE)–SHS Gesellschaft für Beteiligungsmanagement mbH is investing in EIT Emerging Implant Technologies GmbH. EIT was established in Tuttlingen, Germany in 2014 and manufactures spinal implant cages using 3D printing technology. SHS is investing funds from its fourth fund generation to finance EIT’s international growth and development of its innovative products.

3D printing, which is also known as additive manufacturing, is used to manufacture cellular and porous implants of biocompatible titanium. These implants mimic the structure and stiffness of natural bone material more accurately than implants manufactured using traditional methods. This in turn promotes bone ingrowth following fusion operations to achieve better clinical results and reduce complication rates. In addition to this, the implants can be fitted on a patient-specific basis, which serves to increase the contact surface and reduce future risks.

“Our EIT Cellular Titanium implants provide the answer to current challenges in implant design and choice of materials as well the extreme cost pressure in medical technology. The additive manufacturing technology allows us to tackle existing problems with new solutions. Thus we can improve the benefits for patients without increasing costs, which is a clear competitive advantage”, explains Guntmar Eisen, founder and CEO of EIT. “This ensures a high level of patient satisfaction and excellent clinical results. We are looking forward to pushing ahead with our international growth, especially in the United States, and our product development with our new partner SHS.”

“EIT’s 3D-printed spine implants have already proven their superior functionality many times in practical applications, thus promoting EIT’s growth”, adds Dr. Bernhard Schirmers, Managing Partner at SHS Gesellschaft für Beteiligungsmanagement. “EIT Emerging Implant Technologies’ management team is experienced and successful in the field of spine surgery. As a medical technology investor, we look forward to supporting them on their path to increased growth.”

“With SHS, EIT is gaining a shareholder with extensive experience in this industry. Together we can enter the next stage of EIT’s growth. This includes development of the company’s innovative product portfolio as well as entering new countries”, says Guy Selbherr, Managing Director of MBG Mittelständische Beteiligungsgesellschaft Baden-Württemberg.

With a total volume of 125 million euro, the fourth SHS fund is focusing on expansion financing, changes in shareholder structures and successor situations. The Tübingen based investor is planning further acquisitions and investments in the fast-growing medical technology and life-science industries in Germany, Austria and Switzerland in the months ahead.

About EIT Emerging Implant Technologies GmbH:

EIT is the first medical device manufacturer in the orthopedic field to exclusively focus on implants that are designed and produced with additive manufacturing methods.

EIT pushes the boundaries of traditional implant manufacturing to obtain versatile, anatomically designed porous implants with increased functionality and maximal bone ingrowth capabilities for all spinal segments.

The EIT implants made of EIT Cellular Titanium® address the shortcomings of the current designs and materials, thereby ensuring optimal clinical outcomes and maximum patient satisfaction.

EIT provides a complete spinal fusion cage portfolio. Patient specific implants to help in the treatment of complex spinal disorders as well as other interesting implant concepts are in development.

EIT consists of a team of skilled and dedicated professionals with a diverse background in management, research and development and quality assurance. The team has a proven track record setting up and managing innovative spinal implant companies, and has developed an extensive network of contacts over many years including internationally renowned surgeons and opinion leaders in the field of spine surgery.

For further information, visit www.eit-spine.de/

About SHS Gesellschaft für Beteiligungsmanagement mbH

SHS Gesellschaft für Beteiligungsmanagement is based in Tübingen, Germany and invests in medical technology and life science companies with a focus on expansion financing, changes in shareholder structures and successor situations. SHS holds minority as well as majority interests. SHS was founded in 1993 and has since gained extensive experience as industry investor, which supports the growth of its portfolio companies through a network of partnerships regarding the introduction of new products, regulatory issues or entering new markets. The SHS fund’s German and international investors include about the European Investment Fund, professional pension insurers, retirement funds, funds of funds, family offices, entrepreneurs and the SHS management team. The AIFM-registered company is currently investing from its fourth generation of funds, for which investors have provided 125 million euro. Equity of up to 20 million euro is invested. Transactions can be carried out in the mid double-digit million range together with a network of co-investors. Reinhilde Spatscheck, Dr. Bernhard Schirmers, Hubertus Leonhardt and Uwe Steinbacher are the Managing Partners at SHS.

Further information: www.shs-capital.eu

Cerapedics Receives Best New Technology Award for Spine Care at NASS Annual Meeting

WESTMINSTER, Colo., Nov. 18, 2016 /PRNewswire/ — Cerapedics, a privately-held orthobiologics company, today announced it has received a Best New Technology Award for spine care as part of the 2016 Orthopedics This Week Spine Technology Awards. The award recognizes the company’s i-FACTOR™ Peptide Enhanced Bone Graft, the first bone graft to be approved for use in the cervical spine by the U.S. Food and Drug Administration (FDA WESTMINSTER). Award winners were announced in conjunction with the 2016 North American Spine Society (NASS) Annual Meeting, held October 26-29 in Boston, MA.

“Over the past year we have been focused on accelerating our commercialization efforts in the U.S. following the FDA Premarket Approval (PMA) of i-FACTOR Bone Graft,” said Glen Kashuba, CEO of Cerapedics. “We continue to receive outstanding feedback from surgeons across the country who are excited to have a safe, clinically effective and cost effective bone graft that is supported by Level I human data. We are grateful to be recognized by Orthopedics This Week and the surgeon panel who chose i-FACTOR Bone Graft for the Best New Technology Award.”

i‐FACTOR Bone Graft is based on synthetic small peptide (P-15) technology developed by Cerapedics to support bone growth through cell attachment and activation. In November 2015, i-FACTOR Bone Graft was approved by the FDA for use in anterior cervical discectomy and fusion (ACDF) procedures in patients with degenerative cervical disc disease.

The annual Orthopedics This Week Spine Technology Awards honor inventors, engineering teams, surgeons and their companies who have created the most innovative, enduring and practical products to treat back pain. For more information, visit https://ryortho.com/2016/11/the-ten-best-new-spine-technologies-for-2016/.

About Cerapedics

Cerapedics is an orthobiologics company focused on developing and commercializing its proprietary synthetic small peptide (P-15) technology platform. i-FACTOR Peptide Enhanced Bone Graft is the only biologic bone graft in orthopedics that incorporates a small peptide as an attachment factor to stimulate the natural bone healing process. This novel mechanism of action is designed to support safer and more predictable bone formation compared to commercially available bone growth factors. More information can be found at www.cerapedics.com.

Media contact:
Adam Daley
Berry & Company Public Relations
212-253-8881
adaley@berrypr.com

 

SOURCE Cerapedics

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