BASEBALL’S NEXT MIRACLE SURGERY

1-30-2017 – by Will Carroll

“It’s a game changer.”

That phrase is often just hype, but when you hear it come from not one, but four of the top orthopedic surgeons in the country, it’s time to take note.

True changes in sports medicine come about once in a generation. Tommy John surgery, the arthroscope, the use of orthobiologic agents like PRP — these innovations are now part of the sports medicine landscape, and regularly help athletes come back from injuries that were career-altering or even career-ending not that long ago.

The latest new method isn’t on the drawing board; it’s in athletes already. And we’re about to see a lot more of it.

The innovation is really a product, not a surgery. It’s called SutureTape and it’s made by Arthrex, the large medical device manufacturer, after consultation with some of the top orthopedic surgeons. It’s use in surgery is called “InternalBrace.” The tape is affixed during surgery to brace a ligament or reconstruction as it heals, allowing early load and sometimes even return to play prior to complete biologic healing.

Many of the surgeons who consulted Arthrex on the development of SutureTape were on the stage at the recent Lewis Yocum Baseball Medicine Conference, run by the Kerlan-Jobe Clinic and super-surgeon Neil ElAttrache’s staff. A discussion among ElAttrache, Dr. John Conway of the Ben Hogan Clinic in Fort Worth, Dr. Orr Limpisvasti and Dr. Steven Shin of Kerlan-Jobe showed just how much potential this has.

 

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Kuros closes acquisition of Xpand creating a leading commercial-stage orthobiologics company

25 Jan 17

Kuros Biosciences (SIX:KURN) today announced the closing of the all-share strategic acquisition of Xpand Biotechnology B.V. of Bilthoven, the Netherlands. The takeover accelerates Kuros’ transition to commercial stage with two products expected to be ready for commercialization in the European Union this year, one of which may also obtain US approval. In addition, the acquisition provides Kuros with a EU operation with certified and GMP-controlled manufacturing capabilities.

Didier Cowling, CEO of Kuros, commented: “This acquisition provides us with attractive commercial prospects in key orthobiologic market segments as well as an EU hub for our future clinical and distribution operations. We look forward to working with the Xpand team to build an integrated business with promising products on the market and in development.”

Kuros’ first product, MagnetOs granules, is approved for sale in the EU for orthopedics and dental applications. In the US, MagnetOs is under regulatory review for spinal fusion. In addition, a putty formulation is being prepared for submission in the EU and the US in the second half of this year. Neuroseal, a novel biomaterial for dural sealing, is Kuros’ second product and currently under review for CE marking in the EU.

The founders of Xpand, renowned experts and key opinion leaders in the orthobiologics field, remain involved in the combined business and its development. Prof. Joost de Bruijn and Frank-Jan van der Velden remain in their current functions at Xpand as CEO and Managing Director (Mr. de Bruijn) and Head of Business Affairs and Finance (Mr. van der Velden) and join Kuros’ executive management team. Mr. van der Velden and Prof. Clemens van Blitterswijk will be proposed to the next Annual Shareholders’ Meeting as new members of Kuros’ Board of Directors.

Under the terms of the acquisition, Kuros issues a total of up to 2.105 new million shares, of which 1.365 million upon closing of the transaction. The first trading day of these new shares on the SIX Swiss Exchange will be January 25, 2017. A further 0.74 million shares will be issued upon achievement of milestones associated with product approvals.

Bioventus Shares 2017 Science Summit Schedule, Enhancements to Bioventus Academy

January 30, 2017

DURHAM, N.C.–(BUSINESS WIRE)–Bioventus, a global leader in orthobiologics, today announced the dates of its 2017 Advances in Bone Healing Science Summits. Taking place on April 28 at the Grand Hyatt Denver in Denver, CO, on April 28 at the Novotel Schiphol Airport in Amsterdam, and on May 19 at the Westin Fort Lauderdale in Ft. Lauderdale, FL, these programs are geared toward geared towards practitioners who regularly treat fractures and patients with knee osteoarthritis (OA). Each one-day course is developed to allow participants a better understanding of treatment methods and the underlying biologic science through didactic presentations and in-depth case study discussions.

In 2017, Bioventus is also underwriting medical education programs at the American College of Foot and Ankle Surgeons 75th Anniversary Scientific Conference taking place February 27- March 2 in Las Vegas and the Physician Assistants in Orthopaedic Surgery 18th Annual Conference occurring August 21-25 in Baltimore.

In addition, Bioventus has launched several new web-based training courses on www.BioventusAcademy.com. Bioventus Academy is the company’s online medical education platform that provides clinicians with access to in-depth clinical and scientific information on bone healing, bone grafts and OA. The courses are titled: Bone Graft Substitutes, Bone Marrow Aspirate, EXOGEN® & Bone Healing, and DUROLANE® and Early OA Treatment Options.

“Bioventus is committed to becoming the global leader in orthobiologics but leadership is not only measured in sales or global footprint,” said Tony Bihl, CEO, Bioventus. “Furthering medical education for clinicians through both face-to-face and virtual channels underscores the commitment we have to partner with the healthcare community to help people resume and enjoy active lives.”

About Bioventus

Bioventus is an orthobiologics company that delivers clinically proven, cost-effective products that help people heal quickly and safely. Its mission is to make a difference by helping patients resume and enjoy active lives. Bioventus has two product portfolios for orthobiologics, Bioventus Active Healing Therapies and Bioventus Surgical that make it a global leader in active orthopaedic healing. Its EXOGEN Ultrasound Bone Healing System is the #1 prescribed bone healing system in the US and is the only FDA-approved bone healing device that uses safe, effective ultrasound to stimulate the body’s natural healing process. Built on a commitment to high quality standards, evidence-based medicine and strong ethical behavior, Bioventus is a trusted partner for physicians worldwide.

For more information, visit www.BioventusGlobal.com and follow the company on Twitter @Bioventusglobal

Bioventus, the Bioventus logo, DUROLANE and EXOGEN are registered trademarks of Bioventus LLC.

Contacts

Bioventus
Thomas Hill, 919-474-6715
thomas.hill@bioventusglobal.com

 

RTI Surgical Names Camille Farhat Chief Executive Officer

ALACHUA, Fla.–(BUSINESS WIRE)– January 26, 2017

RTI Surgical Inc. (“RTI” or “the company”) (RTIX), a leading global surgical implant company, today announced that Camille Farhat has been named chief executive officer, effective March 15, 2017. He will succeed interim chief executive officer, Robert P. Jordheim, who will resume his role as chief financial officer.

Mr. Farhat, 47, previously served as president and CEO of American Medical Systems, Inc. (AMS), an operating business of Endo International plc (NASDAQ/TSX: ENDP). In this role, he realigned the business to fund innovation, expand internationally and resume growth, ultimately leading to Boston Scientific’s $1.65 billion acquisition of the Men’s and Prostate Health businesses. Mr. Farhat’s expertise aligns with RTI’s focus on developing and delivering exceptional products for patients and achieving sustainable, long-term growth. He has a track record of revitalizing and profitably growing global businesses within the health care industry. Prior to AMS, Mr. Farhat held senior leadership roles where he improved the performance of business units at companies including Baxter Healthcare, Medtronic, Inc. and General Electric.

“Today marks a significant development for RTI’s future. We are pleased that Camille Farhat, an experienced leader with a laser customer focus and solid track record of driving highly effective operational performance in complex health care markets, has agreed to join RTI as our new CEO,” said RTI Chairman Curtis M. Selquist. “On behalf of the entire board, I would like to thank Robert Jordheim for his service as interim CEO. We are pleased that he will be returning to his role as our chief financial officer once Camille is on board. I also want to thank Wy Louw, who has been serving as interim CFO and will resume his controller responsibilities.”

Nicholas J. Valeriani, the RTI board member who led the CEO search process, added, “Following a broad search of both internal and external candidates by RTI’s independent directors, we are confident that Camille has the discipline, talent and demonstrated ability to lead RTI to future success. The company and our customers will benefit from his vibrant leadership, dedication to patients, demand for strategic and operational excellence, and persistent dedication to getting things done and achieving sustainable, long-term growth.”

Mr. Farhat has broad global leadership experience, with senior-level assignments in 10 countries during the past 22 years. Prior to AMS, he advanced several business segments for Baxter. He was global general manager of Baxter’s largest division, Baxter Pharmaceuticals and Therapies, where he drove significant improvements in the performance and operating efficiency of the business, helping to transform it into Baxter’s top-performing business unit. In a previous role, Mr. Farhat successfully turned around Baxter’s Global Infusion Systems business division under a consent decree. Mr. Farhat also served as vice president of business development at Medtronic and as global general manager of the company’s Gastroenterology and Urology divisions. Earlier in his career, Mr. Farhat gained broad executive experience at GE with roles in multiple businesses, geographies and functional areas, leading to his last role as general manager of GE Healthcare’s global Computed Tomography business.

“I am excited to have the opportunity to shape RTI’s strategic direction and return it to sustainable growth,” said Mr. Farhat. “The RTI leadership team, its talented employees and I will dedicate ourselves to developing successful strategies for each business area to ensure we are better addressing our patients’ critical needs and leading the industry in innovation and quality. In doing so, I am confident that we will advance RTI’s path to growth and success.”

Mr. Farhat earned an M.B.A. from Harvard University, a degree in European Union studies from Institut National d’Etudes Politiques de Paris and a B.S., B.A. in finance and accounting from Northeastern University.

RTI’s board worked with Spencer Stuart on the search process.

About RTI Surgical Inc.

RTI Surgical is a leading global surgical implant company providing surgeons with safe biologic, metal and synthetic implants. Committed to delivering a higher standard, RTI’s implants are used in sports medicine, general surgery, spine, orthopedic, trauma and cardiothoracic procedures and are distributed in nearly 50 countries. RTI is headquartered in Alachua, Fla., and has four manufacturing facilities throughout the U.S. and Europe. RTI is accredited in the U.S. by the American Association of Tissue Banks. For more information, please visit www.rtix.com.

Forward Looking Statement

This communication contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on management’s current expectations, estimates and projections about our industry, our management’s beliefs and certain assumptions made by our management. Words such as “anticipates,” “expects,” “intends,” “plans,” “believes,” “seeks,” “estimates,” variations of such words and similar expressions are intended to identify such forward-looking statements. These statements are not guarantees of future performance and are subject to risks and uncertainties, including the risks described in public filings with the U.S. Securities and Exchange Commission (SEC). Our actual results may differ materially from the anticipated results reflected in these forward-looking statements. Copies of the company’s SEC filings may be obtained by contacting the company or the SEC or by visiting RTI’s website at www.rtix.com or the SEC’s website at www.sec.gov.

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Early data demonstrate motor function improvement for spinal cord stem cell treatment

A new therapy to treat spinal cord injuries in people who have lost all motor and sensory function below the injury site has shown additional motor function improvement at six-months and nine-months following treatment with 10 million AST-OPC1. The positive efficacy results from an ongoing clinical research study were revealed in a conference held by Asterias Biotherapeutics, the biotechnology company manufacturing AST-OPC1.

AST-OPC1 cells are made from embryonic stem cells by carefully converting them into oligodendrocyte progenitor cells, which are cells found in the brain and spinal cord that support the healthy functioning of nerve cells and can potentially make poorly functioning nerves function better.

“With these patients, we are seeing what we believe are meaningful improvements in their ability to use their arms, hands and fingers at six months and nine months following AST-OPC1 administration,” says Richard G Fessler, professor in the department of neurosurgery at Rush University Medical Center and lead investigator in the SCiStar Phase 1/2a study. Rush is one of six centres in the country currently studying this new approach.

A total of six patients were enrolled and treated with 10 million AST-OPC1 cells, with five of six patients having now completed a six-month follow-up, and three of six patients having completed a nine-month follow-up.

“Recovery of upper extremity motor function is critically important to patients with complete cervical spinal cord injuries, since this can dramatically improve quality of life and their ability to live independently,” says Fessler.

In September 2016, Fessler reported positive early efficacy data for AST-OPC1 from the patients who have lost all motor and sensory function below injury site that had been treated with 10 million AST-OPC1 cells in the study. The interim research results were announced at the 55th annual Scientific Meeting of the International Spinal Cord Society (ISCOS; 4-16 September 2016, Vienna, Austria).

“We look forward to initiating discussions with the FDA in mid-2017 to begin to determine the most appropriate clinical and regulatory path forward for this innovative therapy,” says Steve Cartt, chief executive officer of Asterias.

 

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Allosource Announces The Annual Dr. Steven Gitelis Inspiration Award

CENTENNIAL, Colo., Jan. 24, 2017 /PRNewswire-USNewswire/ — AlloSource, one of the nation’s largest providers of cartilage, cellular, bone, skin and soft-tissue allografts for use in surgical procedures and wound care to advance patient healing, announced the creation of the Dr. Steven Gitelis Inspiration Award. The award honors a doctor or clinician that inspires AlloSource through his or her work in treating patients with donated human allografts. Dr. Brian Cole of Midwest Orthopaedics at Rush University Medical Center is the inaugural 2017 recipient.

The award’s namesake, Dr. Steven Gitelis, is one of the founding physicians of AlloSource, recognizing the need for donated human tissue to heal patients through his work at Rush University Medical Center.  Through his decades as a highly regarded orthopaedic surgeon, Dr. Gitelis used donated human tissue in complex surgical procedures. He understands the selfless gift of human tissue donation and passes along that gratitude to his patients.

“I’m honored and humbled to have this award named after me,” said Dr. Gitelis. “Dr. Cole and I share the same commitment to advancing medicine for patients and AlloSource has been an important part of this journey.”

Inaugural award recipient Dr. Cole uses allografts to help his patients heal from a variety of injuries and understands the importance of the gift of tissue donation. He is a Professor in the Department of Orthopaedics and a physician at Midwest Orthopaedics at Rush in Chicago, Illinois. He holds a dual appointment as Professor in the Department of Anatomy and Cell Biology and was appointed as Chairman of Surgery at Rush’s Oak Park Hospital in 2011.

“Dr. Cole has been a great partner to AlloSource and a staunch advocate for the use of allografts,” said AlloSource President & CEO, Thomas Cycyota. “We appreciate his dedication to his patients and advancing the science of medicine. Dr. Cole, like Dr. Gitelis, provides healing not only to his patients, but also to tissue donor families by giving them the knowledge that their loved one lives on through donation.”

Founded in 1994, AlloSource is inspired by tissue donors to improve patient healing and advance medicine, serving as a trusted partner for cellular and tissue therapies. By focusing on quality, safety, service and a commitment to its mission, AlloSource has grown into one of the nations’ largest tissue networks in the country.

About AlloSource
AlloSource is one of the largest nonprofit cellular and tissue networks in the country, offering more than 200 types of precise cartilage, cellular, bone, skin and soft-tissue allografts to advance patient healing. For more than 20 years, AlloSource’s products have bridged the proven science of allografts with the advanced technology of cells, offering life-saving and life-enhancing possibilities in spine, sports medicine, foot and ankle, orthopedic, reconstructive, trauma and wound care procedures. As the world’s largest processor of cellular bone allografts, fresh cartilage tissue for joint repair and skin allografts to help heal severe burns, AlloSource delivers unparalleled expertise and service to its growing network of surgeons, partners, and the country’s most reputable organ procurement organizations. The company is accredited by the American Association of Tissue Banks and is headquartered in Centennial, CO. For more information, please visit allosource.org or our educational website, allograftpossibilities.org.

Media Contact
Megan Duggan
AlloSource
720. 382. 2766
mduggan@allosource.org

 

InVivo Therapeutics Announces Sixth Patient Conversion in The INSPIRE Study of the Neuro-Spinal Scaffold™

CAMBRIDGE, Mass.–(BUSINESS WIRE)–

InVivo Therapeutics Holdings Corp. (NVIV) today announced that the patient enrolled in December in the INSPIRE study of the Neuro-Spinal Scaffold has improved from a complete AIS A spinal cord injury to an incomplete AIS B spinal cord injury in the time between discharge and the one-month evaluation. This is the sixth out of the eleven patients (54.5% conversion rate) in follow-up to have had an AIS grade improvement. Two patients who have not yet converted are early in follow-up, with conversion possible before the six-month endpoint. The INSPIRE conversion rate is considerably higher than rates observed in a range of SCI natural history databases.

Domagoj Coric, M.D., of Carolina Neurosurgery and Spine Associates, said: “I have been encouraged by the data generated to date in the INSPIRE study, including the two conversions in patients that I have implanted with the Neuro-Spinal Scaffold.” Dr. Coric, Chief of Neurosurgery at the Carolinas Medical Center and a member of the INSPIRE Study Steering Committee performed the implantation with his partner at Carolina Neurosurgery and Spine Associates, Samuel Chewning, M.D.

“The AIS conversion rate observed thus far in the INSPIRE study has exceeded expectations,” CEO and Chairman Mark Perrin said. “We look forward to following this patient’s progress, and we’re hopeful that we will continue to observe positive INSPIRE results as we work towards completing enrollment.”

About The INSPIRE Study

The INSPIRE Study: InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold™ for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury, is designed to demonstrate the safety and probable benefit of the Neuro-Spinal Scaffold™ for the treatment of complete T2-T12/L1 spinal cord injury in support of a Humanitarian Device Exemption (HDE) application for approval. The FDA has recommended that InVivo include a control arm in the study as part of a Study Design Consideration. We are in discussions with the FDA on this recommendation, and we continue to believe that our current study design is sufficient to demonstrate safety and probable benefit in support of a HDE application for marketing approval. For more information, refer to https://clinicaltrials.gov/ct2/show/study/NCT02138110.

About the Neuro-Spinal Scaffold™ Implant

Following acute spinal cord injury, surgical implantation of the biodegradable Neuro-Spinal Scaffold within the decompressed and debrided injury epicenter is intended to support appositional healing, thereby reducing post-traumatic cavity formation, sparing white matter, and allowing neural regeneration across the healed wound epicenter. The Neuro-Spinal Scaffold, an investigational device, has received a Humanitarian Use Device (HUD) designation and currently is being evaluated in the INSPIRE pivotal probable benefit study for the treatment of patients with complete (AIS A) traumatic acute spinal cord injury.

About InVivo Therapeutics

InVivo Therapeutics Holdings Corp. is a research and clinical-stage biomaterials and biotechnology company with a focus on treatment of spinal cord injuries. The company was founded in 2005 with proprietary technology co-invented by Robert Langer, Sc.D., Professor at Massachusetts Institute of Technology, and Joseph P. Vacanti, M.D., who then was at Boston Children’s Hospital and who now is affiliated with Massachusetts General Hospital. In 2011, the company earned the David S. Apple Award from the American Spinal Injury Association for its outstanding contribution to spinal cord injury medicine. In 2015, the company’s investigational Neuro-Spinal Scaffold received the 2015 Becker’s Healthcare Spine Device Award. The publicly-traded company is headquartered in Cambridge, MA. For more details, visit www.invivotherapeutics.com.

Safe Harbor Statement

Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements within the meaning of the federal securities laws. These statements can be identified by words such as “believe,” “anticipate,” “intend,” “estimate,” “will,” “may,” “should,” “expect,” “designed to,” “potentially,” and similar expressions, and include statements regarding the safety and effectiveness of the Neuro-Spinal Scaffold, the timing of additional enrollments, and the expectation for application for an HDE. Any forward-looking statements contained herein are based on current expectations, and are subject to a number of risks and uncertainties. Factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to the company’s ability to successfully open additional clinical sites for enrollment and to enroll additional patients; the timing of the Institutional Review Board process; the company’s ability to commercialize its products; the company’s ability to develop, market and sell products based on its technology; the expected benefits and efficacy of the company’s products and technology in connection with the treatment of spinal cord injuries; the availability of substantial additional funding for the company to continue its operations and to conduct research and development, clinical studies and future product commercialization; and other risks associated with the company’s business, research, product development, regulatory approval, marketing and distribution plans and strategies identified and described in more detail in the company’s Annual Report on Form 10-K for the year ended December 31, 2015, and its other filings with the SEC, including the company’s Form 10-Qs and current reports on Form 8-K. The company does not undertake to update these forward-looking statements.

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University of Helsinki Finland has developed nanofibers and thin-film biomaterials as orthopedic scaffolds to help regenerate bones and to help implants

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Chemists at the University of Helsinki have created a method of using nanofibers and thin-film biomaterials as orthopedic scaffolds to help regenerate bones and to help implants settle into their new home. The nanofibers are made of electrospun hydroxyapatite, a naturally occuring mineral form of calcium apatite.

Bone is a fibrous nanocomposite material with a complex hierarchical system of different macro-, micro- and nanostructures. The structure elegantly supports the bone cell functions and facilitates bone remodeling by cellular activity. Injuries and diseases, e.g. osteoporosis, can cause bone fractures and loss that need to be treated with orthopedic implants.

In future, it may be possible to use nanofibres to improve the attachment of bone implants, or the fibres may be used directly to scaffold bone regeneration. This would aid the healing of fractures and may enable the care of osteoporosis. This is detailed in a new dissertation.

In his doctoral research, Jani Holopainen of the Department of Chemistry at the University of Helsinki has developed processes for fibrous and thin-film biomaterials that can be used as scaffolding for bone regeneration and in other bone impants. He also studied the apparatus used for nanofibre production.

SYN­THETIC BONE-LIKE MA­TER­IAL
– At best, bone-reforming scaffolds that regenerate at the same rate as bones could be used as implants. The scaffolds activate the bone cells to generate new bone that slowly replaces the disintegrating scaffold and the impant exits the body naturally without separate removal surgery, Jani Holopainen says.

 

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Biology trumps bionics: An alternative to total knee replacement

Published on

If you have severe knee pain or chronic knee inflammation and swelling which cannot be improved by minor surgery or physical therapy, a doctor may recommend that you have total knee replacement surgery. For many people, after years of agony, this operation is a godsend. The procedure relieves pain and greatly enhances their quality of life, allowing them to return to work and resume activities that they have not been able to enjoy in years.

But artificial knee replacements are not a perfect solution. Studies have shown that up to 50% of recipients still have some pain after the procedure. Surgeons are reluctant to perform knee replacements on younger people because the parts don’t last. Subsequent replacements are more complex and wear out even faster.

Many of the arthritic patients I see are under 70 years old and have years of playing sports and being active ahead of them. Therefore I like to do everything possible to rebuild their knee joint with biologic tissues rather than artificial materials to help delay the time in which an artificial joint replacement is necessary.

This regenerative approach to healing is the new frontier in modern medicine as researchers all over the world look for ways to rebuild and regenerate tissues and organs, harnessing the body’s natural ability to heal itself. In many cases these solutions are a long way off, but in orthopedics, we have been practicing them for years.

BioKnee is an alternative to an artificial knee replacement. It combines three key procedures that rebuild, regenerate or biologically replace the damaged parts of the knee.

 

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Bioventus Names John Nosenzo Chief Commercial Officer

January 23, 2017

DURHAM, N.C.–(BUSINESS WIRE)–

Bioventus, a global leader in orthobiologic solutions, today announced that it has named John Nosenzo as Chief Commercial Officer. Nosenzo brings more than 25 years of progressive sales and marketing leadership in pharmaceuticals and medical diagnostic markets to the company. He will be responsible for leading all global sales and distributor management functions for Bioventus, as well as global marketing for the Active Healing Therapies business, and the key customer interface functions responsible for expanding market access for our products and for providing reimbursement services for the EXOGEN® Ultrasound Bone Healing System.

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Nosenzo will report to CEO Tony Bihl and be a member of the Bioventus executive leadership team. He will begin work on February 1.

“John is a natural charismatic leader who develops top talent, builds strong teams, and consistently delivers exceptional sales results,” said Tony Bihl. “We are very pleased he is joining us to lead our commercial organization and look forward to the impact he will make with our customers and our commercial team and processes, to fully capture the global market potential for Bioventus’ expanding product portfolio.”

Prior to joining Bioventus, Nosenzo was Senior Vice President, Global Customer Operations at Beckman Coulter Diagnostics since 2011. Previously, he was Senior Vice President, Customer Relations Management for Siemens Healthcare, and Vice President, Marketing and Sales at Quest Diagnostics.

Nosenzo began his career with Bayer Healthcare, progressively growing thorough sales leadership roles in pharmaceuticals and diagnostic testing businesses over 20+ years, ultimately achieving the role of Senior Vice President, General Manager- Americas for Bayer Diagnostics, prior to the acquisition of this business by Siemens AG.

He earned an MBA in marketing and management from Adelphi University and a Bachelor of Science in pharmacy from St. John’s University.

About Bioventus

Bioventus is an orthobiologics company that delivers clinically proven, cost-effective products that help people heal quickly and safely. Its mission is to make a difference by helping patients resume and enjoy active lives. Bioventus has two product portfolios for orthobiologics, Bioventus Active Healing Therapies and Bioventus Surgical that make it a global leader in active orthopaedic healing. Its EXOGEN Ultrasound Bone Healing System is the #1 prescribed bone healing system in the US and is the only FDA-approved bone healing device that uses safe, effective ultrasound to stimulate the body’s natural healing process. Built on a commitment to high quality standards, evidence-based medicine and strong ethical behavior, Bioventus is a trusted partner for physicians worldwide.

For more information, visit www.BioventusGlobal.com and follow the company on Twitter @Bioventusglobal.

Bioventus, the Bioventus logo and EXOGEN are registered trademarks of Bioventus LLC.

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