Cartiva, Inc., Announces Completion of Patient Enrollment and Treatment in Study of Cartiva® Synthetic Cartilage Implant

Posted On April 27, 2017 By OrthoSpineNews In Extremities, Top Stories /

April 25, 2017

ALPHARETTA, Ga.–(BUSINESS WIRE)–Cartiva, Inc. (Company), a developer of innovative products for treating cartilage damage and osteoarthritis, announced today that it has completed enrollment and treatment of all 50 patients in a multi-center study evaluating the safety and effectiveness of Cartiva Synthetic Cartilage Implant (SCI) for first carpometacarpal (CMC) joint osteoarthritis at the base of the thumb. The study was conducted at nine sites in Canada and the United Kingdom. Basal thumb arthritis is estimated to afflict more than two million American adults, and up to one-third of post-menopausal women.

Cartiva SCI is a proprietary biocompatible polymer device designed to mimic natural cartilage. In July 2016, the Company received Premarket Approval from the FDA for use of Cartiva SCI in the treatment of osteoarthritis at the base of the great toe. The thumb implant treats osteoarthritis in patients with diseased or damaged articular surface in the first CMC joint. It is implanted in the metacarpal base to replace damaged cartilage without destroying or removing healthy tissue. The implant’s design minimizes bone resection while preserving the trapezium. This may provide a quicker, less painful recovery than ligament reconstruction tendon interposition (LRTI) surgery or trapeziectomy.

In late February the Company attended a pre-submission meeting with the Food and Drug Administration (FDA) to discuss this new indication. The Company will review the interim six-month results at an investigator meeting next month.

Mr. Philip Sauve, MB BS, FRCSEd (Tr&Ortho) a Consultant Trauma and Orthopaedic Surgeon at Queen Alexandra Hospital in Portsmouth, England who has treated twelve patients with Cartiva, said “So far we have had good results. Their pain is reducing, their grip strength is increasing and so their function is improving. These early results are very promising but we will have to wait to see how the Cartiva implant performs over a longer period of time. For that group of patients who are maybe still working and still very active, I think it’s a really good option.”

“Cartiva SCI for CMC is a unique product that could greatly benefit patients suffering from this debilitating condition,” said Mr. L. Christopher Bainbridge, MB ChB, FRCSEd, Consultant Hand and Peripheral Nerve Surgeon, Pulvertaft Hand Centre, Royal Derby Hospital, and Chief UK Investigator of the study. “With treatment complete, we are now focused on patient follow-up and data analysis.”

“Completion of on-time enrollment was an important milestone for the Company” said Tim Patrick, president and CEO, Cartiva, Inc. “We look forward to working with FDA to make Cartiva SCI for CMC available in the United States for this promising indication.”

Osteoarthritis of the CMC Joint

Osteoarthritis of the CMC joint— also known as thumb basal joint arthritis,—is a debilitating condition impacting 8% to 12% of the general population and as many as 33% of postmenopausal women. It causes pain, swelling, instability, deformity, loss of motion and weakness, making it difficult to perform a variety of tasks, such as turning doorknobs and opening jars. Current surgical options for later-stage patients for fail conservative treatments include joint fusion, total or partial trapeziectomy, arthroplasty, or LRTI (ligament reconstruction and tendon interposition) which has been done for more than 40 years.

About Cartiva, Inc.

Based in Alpharetta, Ga., Cartiva, Inc. develops and markets innovative solutions for patients with cartilage damage and osteoarthritis. Cartiva’s venture investors include New Enterprise Associates and Windham Venture Partners. Additional information is available on the company’s website at www.cartiva.net.

Contacts

Cartiva, Inc.
Peter Pizzo, 770-754-3855
Chief Financial Officer

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Northwell Announces Affiliation Agreement With Acclaimed Orthopedic Institute

Posted On April 20, 2017 By OrthoSpineNews In Extremities, Sports Medicine, Top Stories /

NEW HYDE PARK, N.Y., April 20, 2017 /PRNewswire-USNewswire/ — Northwell Health has signed a strategic affiliation agreement with the Rothman Institute, one of the nation’s largest, most-prestigious orthopedic practices.

Headquartered in Philadelphia, Pennsylvania, Rothman Institute is known internationally as a preeminent orthopedic and musculoskeletal practice, with more than 25 locations throughout Pennsylvania and New Jersey, including two orthopedic urgent care clinics. Rothman Institute is recognized for their innovative treatment methods, research, education and technology.

The Northwell Health Orthopaedic Institute will be working with Rothman Institute to develop centers of excellence for orthopedic care in the New York Metropolitan area, including Manhattan.

“We’re excited about the affiliation with the Rothman Institute,” said Nicholas Sgaglione, MD, chair of orthopedics at Northwell Health. “The affiliation will bring together two nimble, forward-thinking organizations that emphasize high-quality care. We also look forward to working with the Rothman Institute to co-brand various marketing initiatives, the ongoing recruitment of top-level physicians, joint research, and tracking and measuring patient outcomes.”

“We look forward to joining the Northwell Health family,” said Alexander R. Vaccaro, MD, PhD, MBA, president of Rothman Institute, Richard H. Rothman Professor and chairman of the Department of Orthopaedics, and professor of neurosurgery at Thomas Jefferson University and Hospitals. “This agreement expands Rothman Institute’s footprint into New York City and the surrounding suburbs. We are looking forward to bringing our excellent musculoskeletal care to Northwell Health’s communities and patients now and for years to come.”

About Northwell Health
Northwell Health is New York State’s largest health care provider and private employer, with 21 hospitals and over 550 outpatient practices. We care for more than two million people annually in the metro New York area and beyond, thanks to philanthropic support from our communities. Our 61,000 employees – 15,000+ nurses and nearly 3,400 physicians, including nearly 2,700 members of Northwell Health Physician Partners – are working to change health care for the better. We’re making breakthroughs in medicine at the Feinstein Institute. We’re training the next generation of medical professionals at the visionary Hofstra Northwell School of Medicine and the School of Graduate Nursing and Physician Assistant Studies. And we offer health insurance through CareConnect. For information on our more than 100 medical specialties, visit Northwell.edu.

About Rothman Institute
Rothman Institute is a private orthopaedic practice dedicated to providing communities with high-quality, compassionate, and affordable musculoskeletal care that is grounded in evidence-based medicine, the results of which will exceed expectations. Rothman Institute orthopaedists treat patients at over 25 locations in the Philadelphia-region, including orthopaedic urgent care clinics in Marlton, NJ and Limerick, PA.

With experts in orthopaedic sub-specialties including spine, hip and knee, foot and ankle, shoulder and elbow, hand and wrist, sports medicine, physical medicine and rehabilitation, orthopaedic oncology and trauma, Rothman Institute is internationally recognized for excellence in clinical treatment methods, research, education and technology. Consistently recognized as national and regional “Top Docs,” Rothman Institute is proud to be the first practice serving as official team physicians for all four of the major professional sports teams in one city, the Philadelphia Eagles, Phillies, Flyers and 76ers, as well as over 40 college and high school teams. For more information about Rothman Institute please call 1-800-321-9999 or visit www.RothmanInstitute.com.

SOURCE Northwell Health

Extremity Reconstruction Market : New Business Opportunities & Investment Research Report 2017 – 2025

Posted On April 18, 2017 By OrthoSpineNews In Extremities, Financial /

04-18-2017 – Health & Medicine, Press release from: TMR Research

The global market for extremity reconstruction is expected to witness a high level of growth in the next few years. The rising number of cases of abnormalities and injuries in the lower and upper extremity of the human body is one of the vital factors estimated to encourage the growth of the global market in the coming years. In addition, several advancements in the healthcare infrastructure are anticipated to accelerate the development of the market in the near future. The implant devices for different parts of the human body comprises the extremity reconstruction market in the coming years.

A tremendous rise in the geriatric population and the rising incidences of obesity and diabetes are some of the major factors that are estimated to fuel the development of the global extremity reconstruction market in the near future. Moreover, the increasing cases of osteoarthritis and rheumatoid are likely to accelerate the growth of the market in the coming years. The rising awareness regarding the benefits of small joint reconstruction implants among patients is predicted to encourage the growth of the global extremity reconstruction market in the next few years.

Request a Brochure of the Report @ www.tmrresearch.com/sample/sample?flag=B&rep_id=1175

Technological advancements and the availability of required infrastructure are projected to augment extremity reconstruction market in North America market in the next few years. The leading players operating in the extremity reconstruction market across the globe are emphasizing on introducing innovative implants in order to attract a large number of consumers and attain a leading position in the market. Additionally, the rising level of competition is predicted to expand the product portfolio and benefit the patients in the coming years.

READ THE REST HERE

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HSS Opens Ambulatory Surgery Center in Manhattan

Posted On April 12, 2017 By OrthoSpineNews In Extremities, Sports Medicine /

NEW YORK, N.Y., April 12, 2017 /PRNewswire-USNewswire/ — Today, Hospital for Special Surgery (HSS) the first and only hospital in the United States dedicated to orthopedic and rheumatologic care, announced its plan to open the HSS ASC of Manhattan in June 2017.

The HSS ASC of Manhattan will focus on hand, foot and ankle and sports medicine surgeries. David S. Levine, MD, foot and ankle surgeon at HSS, will serve as the center’s medical director.

“The HSS ASC of Manhattan is a very exciting initiative,” said Dr. Levine. “This new location and offering will substantially expand access to ambulatory surgery as an extension of Hospital for Special Surgery.”

The 22,425 square-foot center is conveniently located at 1233 Second Avenue at 65th Street, a short distance from the Hospital main campus. The center features four operating rooms and a 16 bay pre- and post-surgical unit.

“For nearly three decades HSS has been leading the fields of orthopedics and rheumatology in quality and patient experience,” said Louis A. Shapiro, president and CEO, Hospital for Special Surgery. “HSS is more than a hospital and we’re constantly working to identify news ways to make better quality care more accessible, through research, innovation and locations like this new ASC.”

Bryan Guss, RN, BSN, CNOR, will be the new senior director of the ASC and is joining HSS from Northern Westchester Hospital. HSS physicians on staff at the ASC will include ten sports medicine specialists, five foot and ankle surgeons and five hand and upper extremity surgeons. In addition to the 20 specialty surgeons, there will be anesthesiologists and nursing professionals providing care to patients.

Ambulatory surgery cases will still be performed at the HSS main campus. The HSS ASC of Manhattan is optimizing the care delivery system by providing another surgical location option for patients.

About Hospital for Special Surgery
Hospital for Special Surgery (HSS) is the world’s leading academic medical center focused on musculoskeletal health. HSS is nationally ranked No. 1 in orthopedics and No. 2 in rheumatology by U.S. News & World Report (2016-2017), and is the first hospital in New York State to receive Magnet Recognition for Excellence in Nursing Service from the American Nurses Credentialing Center four consecutive times. HSS has one of the lowest infection rates in the country. HSS is an affiliate of Weill Cornell Medical College and as such all Hospital for Special Surgery medical staff are faculty of Weill Cornell. The Hospital’s research division is internationally recognized as a leader in the investigation of musculoskeletal and autoimmune diseases. Hospital for Special Surgery is located in New York City and online at www.hss.edu.

SOURCE Hospital for Special Surgery

Paragon 28 announces launch of 12 unique titanium wedges to address flatfoot deformities-TITAN 3-D™ Wedge System

Posted On April 10, 2017 By OrthoSpineNews In Extremities, Top Stories /

ENGLEWOOD, Colo., April 6, 2017 /PRNewswire/ — Since its inception, Paragon 28 has obsessed over every aspect of foot and ankle surgery. Committed to creating tailored solutions to improve surgical outcomes, Paragon 28 has launched innovative products and instrumentation that help streamline medical procedures, allow surgeons flexibility in technique and approach, and facilitate reproducible results benefitting both the surgeon and patient.

The TITAN 3-D™ Wedge System builds on Paragon 28’s portfolio of osteotomy wedges and uses the same patented shapes as the PRESERVE™ Evans and Cotton Wedges. These porous titanium wedges offer surgeons an alternative to autograft and allograft bone.

The TITAN 3-D™ Wedges have an open geometry with a three-dimensional scaffold that allows for blood entry, bone through growth, and the incorporation of biologics if used. Each wedge has a central opening which allows for passage of a 3.5 or 4.0mm screw across the osteotomy to help increase stability of the construct. In order to ensure accurate and consistent placement of this crossing screw, both wedge families leverage the patented PRECISION GUIDE™ System. Unlike many competitive implants, Titan 3-D™ Wedges do not require the use of an ancillary surface plate. To increase the coefficient of friction and minimize the chance of implant expulsion, the TITAN 3-D™ wedges are built with spikes which interface with bony surfaces. To facilitate accurate implantation, the system includes product specific inserters which thread onto the back of each wedge and have a strike plate to aid in final seating. The system also includes resection guides which limit excessive bone removal if explanation is required.

Paragon 28 is grateful for the significant contributions Dr. Thomas Chang, DPM Sutter Health, Santa Rosa, CA, made as surgeon designer of this system.

About Paragon 28 Inc.

Paragon 28, Inc was established in 2010 to address the unmet and under-served needs of the foot and ankle community. We believe that through research and innovation we can create new and improved solutions to the challenges faced by foot and ankle specialists.

www.paragon28.com

SOURCE Paragon 28, Inc.

EOS imaging Announces First Sale of EOS System in Israel

Posted On April 6, 2017 By OrthoSpineNews In Extremities, Top Stories /

April 05, 2017

PARIS–(BUSINESS WIRE)–EOS imaging (Paris:EOSI) (Euronext, FR0011191766 – EOSI), the pioneer in 2D/3D orthopedic medical imaging, today announced the first sale of an EOS platform in Israel to Tel Aviv Sourasky Medical Center. The EOS platform has now been sold in 33 countries. The EOS platform is expected to be installed in April at The Dana-Dwek Hospital, one of the four main hospitals that make up the Tel Aviv Sourasky Medical Center.

Tel Aviv Sourasky Medical Center (TAMC) is the second largest and one of the most progressive full-service healthcare treatment and research institutions in Israel. As a premier multidisciplinary academic medical center, the Center serves the greater Tel Aviv metropolitan area population of 3.5 million people accounting for over 42% of the entire population of Israel. TAMC is a national referral center for many major primary and specialty care services.

Marie Meynadier, CEO of EOS imaging, said, “We are pleased that Tel Aviv Sourasky Medical Center is the first site in Israel to acquire an EOS platform. Given its status as a national reference site for orthopedic care, a large number of Israeli patients will now have access to our technology. In addition, this sale further expands our global installed base and provides incremental validation for the EOS system and associated services.”

For more information, please visit www.eos-imaging.com.

EOS imaging has been chosen to be included in the new EnterNext© PEA-PME 150 index, composed of 150 French companies and listed on Euronext and Alternext markets in Paris.

EOS imaging is listed on Compartment C of Euronext Paris
ISIN: FR0011191766 – Ticker: EOSI

About EOS imaging

EOS imaging designs, develops, and markets EOS^®, an innovative medical imaging system dedicated to osteo-articular pathologies and orthopaedics, as well as associated solutions. The Company is authorized to market in 51 countries, including the United States (FDA), Japan and the European Union (EC). The Group posted 2016 revenues of €30.8 million and employs 132 people at December 2016, including an R&D team of 43 engineers. The Group is based in Paris and has five subsidiaries in Besançon (France), Cambridge (Massachusetts), Montreal (Canada), Frankfurt (Germany) and Singapore.

Contacts

EOS imaging
Anne Renevot, +33 (0)1 55 25 61 24
CFO
investors@eos-imaging.com
or
NewCap
Financial communication and investor relations
Pierre Laurent / Valentine Brouchot
+33 (0)1 44 71 94 96
eosimaging@newcap.eu
or
Media Relations
Annie-Florence Loyer
+33 (0)1 44 71 00 12 / 6 88 20 35 59
or
The Ruth Group (US)
Press relations
Joanna Zimmerman, 646-536-7006
jzimmerman@theruthgroup.com

Ottobock Buys Boston-Based “Active” Prosthetic Maker BionX

Posted On April 4, 2017 By OrthoSpineNews In Extremities, Robotics /

David Holley, March 29, 2017

BionX Medical Technologies, a Boston-area company that makes a prosthetic foot and ankle product that uses robotics technology, has been acquired by Ottobock, a German prosthetics company with North American headquarters in Austin, TX.

The deal was announced earlier this month. Financial terms weren’t disclosed, so it’s hard to tell how good an outcome it is for investors and shareholders. BionX raised more than $60 million in equity and debt funding since its inception, including $17 million in late 2015. The company’s investors include General Catalyst, WFD Ventures, Sigma Partners, Gilde Healthcare, and ZGC Shiner Investment.

BionX was founded as iWalk in 2006 by Hugh Herr, an MIT Media Lab professor who runs the school’s Center for Extreme Bionics and who himself is a double amputee below the knees. The company’s device, called the Empower Ankle, uses robotics to propel an amputee forward while adapting to his or her walking style; the actively driven ankle joint tries to replace the function of muscles and tendons. Ottobock says the device can give the user more energy while walking.

READ THE REST HERE

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AMNIOX Study Confirms Benefits of CLARIX FLO for Plantar Fasciitis

Posted On March 30, 2017 By OrthoSpineNews In Extremities /

ATLANTA–(BUSINESS WIRE)–

AMNIOX Medical, Inc., a TissueTech, Inc. company, announced today the results of a study demonstrating the application of its unique cryopreserved human umbilical cord tissue for the treatment of patients with plantar fasciitis. The findings were recently presented at the American College of Foot and Ankle Surgeons in Las Vegas.

In this study, forty-three patients received injections of CLARIX FLO human amniotic membrane and umbilical cord matrix, and were followed for 18 weeks. The authors concluded that injections of CLARIX FLO significantly decreased pain from baseline and improved overall functional recovery. Increasing dose resulted in better therapy outcomes.

The study, Particulate Umbilical Cord/Amniotic Membrane for the Treatment of Plantar Fasciitis, was authored by Dr. Ryan Scott of The CORE Institute in Phoenix, and Dr. David Garras of Midwest Orthopaedic Consultants and an Assistant Professor at University of Illinois at Chicago. Plantar fasciitis is the most common cause of debilitating heal pain. It affects up to 1 million patients annually in the United States and as many as 30 percent of those patients fail conservative therapy. The condition is characterized by an accumulation of small tears in the plantar fascia, causing the structure to weaken and become irritated, often to the point of interfering in daily activities. Previously available therapies have demonstrated inconsistent outcomes or have negative side effects.

“These study results continue to demonstrate the compelling therapeutic benefits of a human tissue matrix composed of both umbilical cord and amniotic membrane,” said Tom Dugan, Chief Executive Officer of Amniox Medical. “Furthermore, Amniox Medical is the only provider of an injectable form of umbilical cord, allowing for the non-invasive delivery of the biological components of umbilical cord, which have proven regenerative properties.”

In utero, wound healing occurs rapidly and with minimal scar. This restorative ability is innate to placental tissues, including umbilical cord and amniotic membrane. Heavy chain hyaluronic acid/pentraxin-3 is the key protein complex present in these tissues to orchestrate the healing process. Amniox Medical is the first provider of a human tissue allograft composed of both umbilical cord and amniotic membrane. Amniox utilizes its proprietary CryoTek™ process, a cryopreservation technology, to preserve the biological and structural integrity of the native tissue and published studies have demonstrated that the CryoTek process more effectively preserves the structural and biological integrity of the tissue.

About Amniox Medical, Inc.

Founded in 2011 to serve the orthopedic and wound care markets, Amniox Medical is dedicated to developing and marketing regenerative therapies processed from umbilical cord and amniotic membrane utilizing its proprietary CryoTek technology. This process has been proven to preserve the innate biological and structural properties of the matrix, which can then be transplanted to adult wound and surgical environments. Amniox Medical procures its tissue through elective donation following healthy live birth via Cesarean section. Thorough donor screening is performed to ensure safety of its products. For additional information, please visit http://www.amnioxmedical.com

About TissueTech, Inc.

TissueTech, Inc., the parent company of Amniox Medical, Inc. and Bio-Tissue^®, Inc., pioneered the development and clinical application of regenerative, amniotic tissue-based products. Amniox Medical develops and markets products for use in the musculoskeletal and wound care markets; Bio-Tissue develops and markets products for the ophthalmology and optometry markets. The National Institutes of Health (NIH) have supported TissueTech’s research with more than 30 continuous years of research grants. Since the company’s inception, clinicians have performed more than 250,000 human implants of the company’s products and published more than 300 peer-reviewed studies supporting its technology platform. The Company’s first product, AmnioGraft^®, is the only tissue graft designated by the FDA as homologous for promoting ophthalmic wound healing while suppressing scarring and inflammation.

View source version on businesswire.com: http://www.businesswire.com/news/home/20170330005905/en/

Medeon Biodesign Announces Investing in Panther Orthopedics for Orthopedic Extremity Applications

Posted On March 29, 2017 By OrthoSpineNews In Extremities, Financial /

TAIPEI, Taiwan, March 28, 2017 /PRNewswire/ — Medeon Biodesign, Inc., a Taiwan medical device company, is pleased to announce that the Company led and successfully closed the Series A investment of Panther Orthopedics, Inc., a San Jose, CA start-up pioneering innovative dynamic fixation solutions for orthopedic extremity applications.

The orthopedic extremity device market continues to expand rapidly, primarily due to procedure volume growth, lifestyle influences and favorable demographics. Nevertheless, the market need for better fixation products for both trauma and sports medicine in fracture fixation and joint stabilization applications is still under served. “Current options for fixation include cortical screw and suture button flexible fixation devices. However, many limitations associated with currently marketed products are not being addressed,” said Dr. Kathryn Stecco, CEO and co-founder of Panther Orthopedics. “We have developed an innovative platform for dynamic extremity fixation, which we believe will provide continuous compression during the healing period while still allowing micromotion. The intuitive design of our solutions is easy to use and intended to eliminate the need for most second surgery removal, providing significant benefits for both the patients and the entire healthcare system.”

“We are excited to lead the investment of Panther Orthopedics to address the long-standing need of better clinical fixation during the healing period for orthopedic extremity applications,” said Dr. Yue-Teh Jang, CEO of Medeon Biodesign. “We are impressed with the team’s extensive experience, profound knowledge of orthopedic applications and broad KOL networking. We are confident that the Panther Orthopedics’ unique and innovative dynamic fixation solutions will be very welcome by the clinical community in the near future.”

About Medeon Biodesign

Medeon Biodesign (TPEx: 6499) is a publicly traded company located in Taipei, Taiwan, and currently listed on Taipei Exchange. The company focuses on the development of medical devices for minimally invasive surgeries to treat diseases of sizable patient population, such as cardiovascular, peripheral vascular, orthopedic, neurosurgery, obesity, gastroenterology, hematology, nephrology, gynecology, urology, and plastic surgery. For more information, please visit www.medeonbio.com/en.

Contacts
Dr. Yi-Ju Chen
+886.2.2881.6686
ir@medeonbio.com

SOURCE Medeon Biodesign, Inc.

Integra LifeSciences Announces Commercial Expansion of the Cadence® Total Ankle System

Posted On March 29, 2017 By OrthoSpineNews In Extremities, Top Stories /

PLAINSBORO, N.J., March 28, 2017 (GLOBE NEWSWIRE) — Integra LifeSciences Holdings Corporation (NASDAQ:IART), a leading global medical technology company, today announced full commercial availability of its Cadence^® Total Ankle System, a new ankle prosthesis developed in partnership with four world leading foot and ankle surgeons – Dr. Tim Daniels (University of Toronto), Dr. David Pedowitz (Rothman Institute, Philadelphia, Pa.), Dr. Selene Parekh (Duke University, Durham, N.C.) and Dr. Christopher Hyer (Orthopedic Foot & Ankle Center, Westerville, Ohio).

More than 200 Cadence total ankle procedures have been successfully performed in seven countries, since initial clinical use more than a year ago. During this period, instrumentation updates and enhanced surgeon training were introduced, designed to further improve quality, patient safety, and procedural efficiency of the system.

Integra completed corrective actions required to close an FDA recall related to the clarification of the system surgical technique, which addressed a small percentage of intra-operative posterior tibial fractures occurring due to technique error. The recall required no return of product, and since the implementation of the clarified surgical technique, no subsequent posterior tibial fractures have occurred in more than 100 procedures.

The Cadence system has garnered positive feedback among its users for advancements in implant and instrument design, along with a streamlined surgical technique. Cadence incorporates several features to accommodate various patient anatomies, reduce potential clinical complications, and address common challenges associated with ankle arthroplasty procedure. Key implant features include:

Side-specific, anatomical tibial components, designed to avoid fibular impingement.
Side-specific, anatomical talar components, designed to minimize resected talar bone and to preserve vascularity in the ankle.
Bearing insert components manufactured from a highly crosslinked ultra-high molecular weight polyethylene (HXL UHMWPE) for improved wear characteristics, and patent pending-biased sagittal profile options to address patients with subluxed talar anatomy.

“I’ve implanted over 50 Cadence Total Ankle prostheses. I am very impressed with the versatility, reliability, reproducibility, and short-term outcomes of this implant,” said Dr. Tim Daniels. “The streamlined and reliable operative instruments and techniques of this procedure, combined with an anatomical design, offer significant advantages over other ankle systems on the market today.”

The Cadence Total Ankle System was previously available in a limited market release. The Cadence system is now fully available in the United States, Canada, and select European countries. Integra plans to initiate several global post-market clinical studies with the Cadence system to further support product efficacy.

About Integra
Integra LifeSciences is dedicated to limiting uncertainty for clinicians, so they can concentrate on providing the best patient care. Integra offers innovative solutions, including leading plastic and regenerative technologies, in specialty surgical solutions, orthopedics and tissue technologies. For more information, please visit www.integralife.com.

This news release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements concerning the products and services provided by Integra. Such forward looking statements involve risks and uncertainties that could cause actual results to differ materially from predicted or expected results. Among other things, the willingness of surgical professionals to use Integra products may affect the prospects for their use in surgical procedures. In addition, the economic, competitive, governmental, technological and other factors, identified under the heading “Risk Factors” included in Item IA of Integra’s Annual Report on Form 10-K for the year ended December 31, 2015 and information contained in subsequent filings with the Securities and Exchange Commission could affect actual results.

CONTACT: Integra LifeSciences Holdings Company

Investors
Angela Steinway
609-936-2268
angela.steinway@integralife.com

Michael Beaulieu
609-750-2827
michael.beaulieu@integralife.com

Media
Laurene Isip
609-750-7984
laurene.isip@integralife.com

Extremities

Cartiva, Inc., Announces Completion of Patient Enrollment and Treatment in Study of Cartiva® Synthetic Cartilage Implant

Contacts

Northwell Announces Affiliation Agreement With Acclaimed Orthopedic Institute

Related Links

Extremity Reconstruction Market : New Business Opportunities & Investment Research Report 2017 – 2025

HSS Opens Ambulatory Surgery Center in Manhattan

Related Links

Paragon 28 announces launch of 12 unique titanium wedges to address flatfoot deformities-TITAN 3-D™ Wedge System

Related Links

EOS imaging Announces First Sale of EOS System in Israel

Contacts

Ottobock Buys Boston-Based “Active” Prosthetic Maker BionX

AMNIOX Study Confirms Benefits of CLARIX FLO for Plantar Fasciitis

Medeon Biodesign Announces Investing in Panther Orthopedics for Orthopedic Extremity Applications

Related Links

Integra LifeSciences Announces Commercial Expansion of the Cadence® Total Ankle System